Acetamide,N-(2-aminophenyl)- CAS NO.34801-09-7

The Acetamide, N-(2-aminophenyl)-, with the CAS registry number of 34801-09-7, is also known as 2-Aminoacetanilide and o-Aminoacetanilide. It belongs to the product categories of Amineprimary; Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Benzenes; Nitrogen Compounds; Organic Building Blocks; Protected Amines. This chemical's molecular formula is C₈H₁₀N₂O and molecular weight is 150.18. What's more, its IUPAC name is N-(2-Aminophenyl)acetamide. In addition, it must be stored in airtight containers and placed in a dry, cool, place. Meanwhile, it should avoid contact with oxidant. Besides, ensure the work place is well-ventilated.

Physical properties about Acetamide, N-(2-aminophenyl)-are: (1)ACD/LogP: 0.13; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.11; (4)ACD/LogD (pH 7.4): 0.13; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 26.77; (8)ACD/KOC (pH 7.4): 27.97; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 23.55 Å²; (13)Index of Refraction: 1.636; (14)Molar Refractivity: 44.76 cm³; (15)Molar Volume: 124.7 cm³; (16)Polarizability: 17.74×10^-24 cm³; (17)Surface Tension: 53 dyne/cm; (18)Density: 1.203 g/cm³; (19)Flash Point: 172.4 °C; (20)Enthalpy of Vaporization: 60.74 kJ/mol; (21)Boiling Point: 361.5 °C at 760 mmHg; (22)Vapour Pressure: 2.06E-05 mmHg at 25 °C; (23)Melting Point: 133-137 °C(lit. ).

Preparation: this chemical is prepared by N-(2-Nitro-phenyl)-acetamide. This reaction needs reagents NH₄Cl and Raney nickel. Meanwhile, it needs solvent H₂O. The reaction time is 2.1 hours with reaction temperature of 80-90 °C. The yield is about 91 %.

Uses: it is used to produce other chemicals. For example, it is used to produce 2-Methyl-1H-benzoimidazole at heating. The reaction needs reagent AcOH and solvent Xylene. The yield is about 97 %.

The Acetamide, N-(2-aminophenyl)-, with the CAS registry number of 34801-09-7, is also known as 2-Aminoacetanilide and o-Aminoacetanilide. It belongs to the product categories of Amineprimary; Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Benzenes; Nitrogen Compounds; Organic Building Blocks; Protected Amines. This chemical's molecular formula is C₈H₁₀N₂O and molecular weight is 150.18. What's more, its IUPAC name is N-(2-Aminophenyl)acetamide. In addition, it must be stored in airtight containers and placed in a dry, cool, place. Meanwhile, it should avoid contact with oxidant. Besides, ensure the work place is well-ventilated.

Physical properties about Acetamide, N-(2-aminophenyl)-are: (1)ACD/LogP: 0.13; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.11; (4)ACD/LogD (pH 7.4): 0.13; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 26.77; (8)ACD/KOC (pH 7.4): 27.97; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 23.55 Å²; (13)Index of Refraction: 1.636; (14)Molar Refractivity: 44.76 cm³; (15)Molar Volume: 124.7 cm³; (16)Polarizability: 17.74×10^-24 cm³; (17)Surface Tension: 53 dyne/cm; (18)Density: 1.203 g/cm³; (19)Flash Point: 172.4 °C; (20)Enthalpy of Vaporization: 60.74 kJ/mol; (21)Boiling Point: 361.5 °C at 760 mmHg; (22)Vapour Pressure: 2.06E-05 mmHg at 25 °C; (23)Melting Point: 133-137 °C(lit. ).

Preparation: this chemical is prepared by N-(2-Nitro-phenyl)-acetamide. This reaction needs reagents NH₄Cl and Raney nickel. Meanwhile, it needs solvent H₂O. The reaction time is 2.1 hours with reaction temperature of 80-90 °C. The yield is about 91 %.

Uses: it is used to produce other chemicals. For example, it is used to produce 2-Methyl-1H-benzoimidazole at heating. The reaction needs reagent AcOH and solvent Xylene. The yield is about 97 %.