China (Mainland)
Acetamide,N-[2-(1H-indol-3-yl)ethyl]- CAS NO.1016-47-3
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Keywords
- N-[2-(1H-Indol-3-yl)ethyl]acetamide
- Acetamide,N-(2-indol-3-ylethyl)- (7CI,8CI)
- Acetamide,N-(2-indol-3-ylethyl)- (7CI,8CI)
Quick Details
- ProName: Acetamide,N-[2-(1H-indol-3-yl)ethyl]-
- CasNo: 1016-47-3
- Application: The Acetamide,N-[2-(1H-indol-3-yl)ethy...
- ProductionCapacity: Metric Ton/Day
- Purity: 99
- Transportation: The Acetamide,N-[2-(1H-indol-3-yl)ethy...
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Superiority
The Acetamide,N-[2-(1H-indol-3-yl)ethyl]-, with the CAS registry number 1016-47-3, is also known as 3-(2-N-Acetylaminoethyl)indole. This chemical's molecular formula is C12H14N2O and molecular weight is 202.25. What's more, its systematic name is N-[2-(1H-indol-3-yl)ethyl]acetamide. It should be sealed and stored in cool and dry places and stored at the temperature of 2-8 °C.
Physical properties of Acetamide,N-[2-(1H-indol-3-yl)ethyl]- are: (1)ACD/LogP: 1.05; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.05; (4)ACD/LogD (pH 7.4): 1.05; (5)ACD/BCF (pH 5.5): 3.68; (6)ACD/BCF (pH 7.4): 3.68; (7)ACD/KOC (pH 5.5): 88.43; (8)ACD/KOC (pH 7.4): 88.43; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 25.24 Å2; (13)Index of Refraction: 1.619; (14)Molar Refractivity: 60.96 cm3; (15)Molar Volume: 173.6 cm3; (16)Polarizability: 24.16 ×10-24cm3; (17)Surface Tension: 49.2 dyne/cm; (18)Density: 1.164 g/cm3; (19)Flash Point: 246.9 °C; (20)Enthalpy of Vaporization: 75 kJ/mol; (21)Boiling Point: 484.7 °C at 760 mmHg; (22)Vapour Pressure: 1.51E-09 mmHg at 25°C.
Preparation: this chemical can be prepared by 2-indol-3-yl-ethylamine and acetic acid anhydride at the temperature of 20-25 °C. This reaction will need the reaction time of 15 min. The yield is about 72%.
![Acetamide,N-[2-(1H-indol-3-yl)ethyl]- can be prepared by 2-indol-3-yl-ethylamine and acetic acid anhydride](http://www.lookchem.com/UserFilesUpload/Preparation%20of%20Acetamide,n-[2-(1h-indol-3-yl)ethyl]-(1).jpg)
Uses of Acetamide,N-[2-(1H-indol-3-yl)ethyl]-: it can be used to produce 1-methyl-4,9-dihydro-3H-b-carboline. It will need reagents POCl3, P2O5 and solvent acetonitrile with the reaction time of 160 s. This reaction also needs microwave irradiation. The yield is about 86%.
Details
The Acetamide,N-[2-(1H-indol-3-yl)ethyl]-, with the CAS registry number 1016-47-3, is also known as 3-(2-N-Acetylaminoethyl)indole. This chemical's molecular formula is C12H14N2O and molecular weight is 202.25. What's more, its systematic name is N-[2-(1H-indol-3-yl)ethyl]acetamide. It should be sealed and stored in cool and dry places and stored at the temperature of 2-8 °C.
Physical properties of Acetamide,N-[2-(1H-indol-3-yl)ethyl]- are: (1)ACD/LogP: 1.05; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.05; (4)ACD/LogD (pH 7.4): 1.05; (5)ACD/BCF (pH 5.5): 3.68; (6)ACD/BCF (pH 7.4): 3.68; (7)ACD/KOC (pH 5.5): 88.43; (8)ACD/KOC (pH 7.4): 88.43; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 25.24 Å2; (13)Index of Refraction: 1.619; (14)Molar Refractivity: 60.96 cm3; (15)Molar Volume: 173.6 cm3; (16)Polarizability: 24.16 ×10-24cm3; (17)Surface Tension: 49.2 dyne/cm; (18)Density: 1.164 g/cm3; (19)Flash Point: 246.9 °C; (20)Enthalpy of Vaporization: 75 kJ/mol; (21)Boiling Point: 484.7 °C at 760 mmHg; (22)Vapour Pressure: 1.51E-09 mmHg at 25°C.
Preparation: this chemical can be prepared by 2-indol-3-yl-ethylamine and acetic acid anhydride at the temperature of 20-25 °C. This reaction will need the reaction time of 15 min. The yield is about 72%.
Uses of Acetamide,N-[2-(1H-indol-3-yl)ethyl]-: it can be used to produce 1-methyl-4,9-dihydro-3H-b-carboline. It will need reagents POCl3, P2O5 and solvent acetonitrile with the reaction time of 160 s. This reaction also needs microwave irradiation. The yield is about 86%.