Acetic acid,2-phosphono- CAS NO.4408-78-0

The Acetic acid,2-phosphono-, with the CAS registry number 4408-78-0, is also known as Carboxymethanephosphonic acid. It belongs to the product categories of Phosphonic/Phosphinic Acids Enzyme Inhibitors by Enzyme; Proline Dipeptidase; Organic Building Blocks; P to; Phosphorus Compounds. Its EINECS registry number is 224-558-1. This chemical's molecular formula is C₂H₅O₅P and molecular weight is 140.031861. Its IUPAC name is called 2-phosphonoacetic acid. This chemical's classification codes are Anti-Infective Agents; Anti-Retroviral Agents; Antiviral Agents; Enzyme inhibitors; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors. It is white powder. The product should be sealed and stored in dry and well-ventilated place.

Physical properties of Acetic acid,2-phosphono-: (1)ACD/LogP: -2.38; (2)ACD/LogD (pH 5.5): -6.51; (3)ACD/LogD (pH 7.4): -7.17; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 5; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.517; (12)Molar Refractivity: 22.82 cm³; (13)Molar Volume: 75.3 cm³; (14)Surface Tension: 101.4 dyne/cm; (15)Density: 1.858 g/cm³; (16)Flash Point: 250.2 °C; (17)Enthalpy of Vaporization: 82.85 kJ/mol; (18)Boiling Point: 490.2 °C at 760 mmHg; (19)Vapour Pressure: 6E-11 mmHg at 25°C.

Preparation: this chemical can be prepared by diethoxyphosphoryl-acetic acid ethyl ester. This reaction will need reagent aq. HCl.

Uses of Acetic acid,2-phosphono-: it can be used to produce 1-(dimethylamino)-2,2-bis[(dimethylimmonio)-methyl]ethene diperchlorate at temperature of 110 - 120 °C. This reaction will need reagent POCl₃ with reaction time of 2 hours. The yield is about 59%.

The Acetic acid,2-phosphono-, with the CAS registry number 4408-78-0, is also known as Carboxymethanephosphonic acid. It belongs to the product categories of Phosphonic/Phosphinic Acids Enzyme Inhibitors by Enzyme; Proline Dipeptidase; Organic Building Blocks; P to; Phosphorus Compounds. Its EINECS registry number is 224-558-1. This chemical's molecular formula is C₂H₅O₅P and molecular weight is 140.031861. Its IUPAC name is called 2-phosphonoacetic acid. This chemical's classification codes are Anti-Infective Agents; Anti-Retroviral Agents; Antiviral Agents; Enzyme inhibitors; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors. It is white powder. The product should be sealed and stored in dry and well-ventilated place.

Physical properties of Acetic acid,2-phosphono-: (1)ACD/LogP: -2.38; (2)ACD/LogD (pH 5.5): -6.51; (3)ACD/LogD (pH 7.4): -7.17; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 5; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.517; (12)Molar Refractivity: 22.82 cm³; (13)Molar Volume: 75.3 cm³; (14)Surface Tension: 101.4 dyne/cm; (15)Density: 1.858 g/cm³; (16)Flash Point: 250.2 °C; (17)Enthalpy of Vaporization: 82.85 kJ/mol; (18)Boiling Point: 490.2 °C at 760 mmHg; (19)Vapour Pressure: 6E-11 mmHg at 25°C.

Preparation: this chemical can be prepared by diethoxyphosphoryl-acetic acid ethyl ester. This reaction will need reagent aq. HCl.

Uses of Acetic acid,2-phosphono-: it can be used to produce 1-(dimethylamino)-2,2-bis[(dimethylimmonio)-methyl]ethene diperchlorate at temperature of 110 - 120 °C. This reaction will need reagent POCl₃ with reaction time of 2 hours. The yield is about 59%.