China (Mainland)
Acetamide,2-chloro-N-(2,4-difluorophenyl)- CAS NO.96980-65-3
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- Product Details
Keywords
- C8H6ClF2NO
- C8H6ClF2NO
- C8H6ClF2NO
Quick Details
- ProName: Acetamide,2-chloro-N-(2,4-difluorophen...
- CasNo: 96980-65-3
- Molecular Formula: C8H6ClF2NO
- Application: The Acetamide,2-chloro-N-(2,4-difluoro...
- ProductionCapacity: Metric Ton/Day
- Purity: 99
- Transportation: The Acetamide,2-chloro-N-(2,4-difluoro...
- LimitNum: 0 Metric Ton
Superiority
The Acetamide,2-chloro-N-(2,4-difluorophenyl)- is an organic compound with the formula C8H6ClF2NO. The IUPAC name of this chemical is 2-chloro-N-(2,4-difluorophenyl)acetamide. With the CAS registry number 96980-65-3, it is also named as N1-(2,4-difluorophenyl)-2-chloroacetamide.
The other characteristics of this product can be summarized as: (1)ACD/LogP: 1.87; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.87; (4)ACD/LogD (pH 7.4): 1.87; (5)ACD/BCF (pH 5.5): 15.61; (6)ACD/BCF (pH 7.4): 15.61; (7)ACD/KOC (pH 5.5): 248.85; (8)ACD/KOC (pH 7.4): 248.75; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.55; (13)Molar Refractivity: 45.36 cm3; (14)Molar Volume: 142.3 cm3; (15)Polarizability: 17.98×10-24 cm3; (16)Surface Tension: 42.6 dyne/cm; (17)Enthalpy of Vaporization: 55.42 kJ/mol; (18)Vapour Pressure: 0.000506 mmHg at 25°C; (19)Rotatable Bond Count: 2; (20)Tautomer Count: 2; (21)Exact Mass: 205.010598; (22)MonoIsotopic Mass: 205.010598; (23)Topological Polar Surface Area: 29.1; (24)Heavy Atom Count: 13; (25)Complexity: 191.
Preparation of Acetamide,2-chloro-N-(2,4-difluorophenyl)-: It can be obtianed by chloroacetyl chloride and 2,4-difluoro-aniline. This reaction needs reagent Et3N and solvent tetrahydrofuran at temperature of 0 °C. The reaction time is 10 hours. The yield is 99%.
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Uses of Acetamide,2-chloro-N-(2,4-difluorophenyl)-: It can react with 2-mercapto-1-phenyl-ethanone to get N-(2,4-difluoro-phenyl)-2-(2-oxo-2-phenyl-ethylsulfanyl)-acetamide. This reaction needs reagent K2CO3 and solvent tetrahydrofuran at temperature of 50 °C. The reaction time is 6 hours. The yield is 88%.
Details
The Acetamide,2-chloro-N-(2,4-difluorophenyl)- is an organic compound with the formula C8H6ClF2NO. The IUPAC name of this chemical is 2-chloro-N-(2,4-difluorophenyl)acetamide. With the CAS registry number 96980-65-3, it is also named as N1-(2,4-difluorophenyl)-2-chloroacetamide.
The other characteristics of this product can be summarized as: (1)ACD/LogP: 1.87; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.87; (4)ACD/LogD (pH 7.4): 1.87; (5)ACD/BCF (pH 5.5): 15.61; (6)ACD/BCF (pH 7.4): 15.61; (7)ACD/KOC (pH 5.5): 248.85; (8)ACD/KOC (pH 7.4): 248.75; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.55; (13)Molar Refractivity: 45.36 cm3; (14)Molar Volume: 142.3 cm3; (15)Polarizability: 17.98×10-24 cm3; (16)Surface Tension: 42.6 dyne/cm; (17)Enthalpy of Vaporization: 55.42 kJ/mol; (18)Vapour Pressure: 0.000506 mmHg at 25°C; (19)Rotatable Bond Count: 2; (20)Tautomer Count: 2; (21)Exact Mass: 205.010598; (22)MonoIsotopic Mass: 205.010598; (23)Topological Polar Surface Area: 29.1; (24)Heavy Atom Count: 13; (25)Complexity: 191.
Preparation of Acetamide,2-chloro-N-(2,4-difluorophenyl)-: It can be obtianed by chloroacetyl chloride and 2,4-difluoro-aniline. This reaction needs reagent Et3N and solvent tetrahydrofuran at temperature of 0 °C. The reaction time is 10 hours. The yield is 99%.
Uses of Acetamide,2-chloro-N-(2,4-difluorophenyl)-: It can react with 2-mercapto-1-phenyl-ethanone to get N-(2,4-difluoro-phenyl)-2-(2-oxo-2-phenyl-ethylsulfanyl)-acetamide. This reaction needs reagent K2CO3 and solvent tetrahydrofuran at temperature of 50 °C. The reaction time is 6 hours. The yield is 88%.